Average Nurse practitioners Salary in Manchester
ONS ASHE 2025 · North West region · Updated October 2025
How Manchester compares
The median pay for nurse practitionerss in the North West stood at £41,159 in 2025, placing them 0.6% below the UK-wide figure of £41,392. This is particularly notable given ongoing NHS recruitment challenges and rising demand for healthcare staff. In practical terms, living costs in the North West run 8.8% below average. That means £41,159 stretches to roughly £45,130 in real spending power. Compared to the Manchester average across all roles (£36,554), nurse practitionerss take home 12.6% more.
Cost of Living Adjustment
After adjusting for the regional cost of living (North West index: 91.2, UK=100), a salary of £41,159 has an effective purchasing power of approximately £45,130 — equivalent to earning that amount in an area with average UK costs. The cost of living in the North West is 8.8% below the UK average.
Nurse practitioners salary across UK regions
Nurse practitioners salary in areas near Manchester
Salary data is by ONS region. Manchester is in the North West region. Below are neighbouring regions — click to explore salaries there.
Nurse practitioners Salary Guide
The full salary guide includes regional breakdowns, cost-of-living adjustments, year-on-year trends, and in-depth FAQs.
Read the full Nurse practitioners salary guide →Find Nurse practitioners jobs in Manchester
Explore roles paying around £41,159/year
Frequently Asked Questions
What is the average nurse practitioners salary in Manchester?
The median nurse practitioners salary in the North West (which includes Manchester) is £41,159 per year, based on ONS ASHE 2025 data. The mean salary is typically higher due to top earners pulling the average up.
How does nurse practitioners pay in Manchester compare to the UK average?
Nurse practitioners in the North West earn 0.6% below the national median of £41,392. Other regions such as London and the South East typically offer higher salaries for this role.
Is nurse practitioners a well-paid job in Manchester compared to other roles?
The average salary across all jobs in Manchester is £36,554. Nurse practitioners in the North West earn £41,159, which is 12.6% above the local average across all occupations.
About this data
Salary figures for nurse practitionerss cover the North West region. The all-jobs average is specific to Manchester. Source: ONS ASHE 2025. Methodology.