Average Specialist nurses Salary in Manchester
ONS ASHE 2025 · North West region · Updated October 2025
How Manchester compares
The going rate for specialist nursess in the North West? £45,568 at the median in 2025. That compares to £41,095 nationally — a gap of 10.9% above. Factor in the North West's cost of living (8.8% below the UK norm) and a £45,568 salary has the purchasing power of approximately £49,965. To put this alongside local pay more broadly: the average across all jobs in Manchester is £36,554, so specialist nursess sit 24.7% more that benchmark.
Cost of Living Adjustment
After adjusting for the regional cost of living (North West index: 91.2, UK=100), a salary of £45,568 has an effective purchasing power of approximately £49,965 — equivalent to earning that amount in an area with average UK costs. The cost of living in the North West is 8.8% below the UK average.
Specialist nurses salary across UK regions
Specialist nurses salary in areas near Manchester
Salary data is by ONS region. Manchester is in the North West region. Below are neighbouring regions — click to explore salaries there.
Specialist nurses Salary Guide
The full salary guide includes regional breakdowns, cost-of-living adjustments, year-on-year trends, and in-depth FAQs.
Read the full Specialist nurses salary guide →Find Specialist nurses jobs in Manchester
Explore roles paying around £45,568/year
Frequently Asked Questions
What is the average specialist nurses salary in Manchester?
The median specialist nurses salary in the North West (which includes Manchester) is £45,568 per year, based on ONS ASHE 2025 data. The mean salary is typically higher due to top earners pulling the average up.
How does specialist nurses pay in Manchester compare to the UK average?
Specialist nurses in the North West earn 10.9% above the national median of £41,095. This makes the North West one of the higher-paying regions for this role.
Is specialist nurses a well-paid job in Manchester compared to other roles?
The average salary across all jobs in Manchester is £36,554. Specialist nurses in the North West earn £45,568, which is 24.7% above the local average across all occupations.
About this data
Salary figures for specialist nursess cover the North West region. The all-jobs average is specific to Manchester. Source: ONS ASHE 2025. Methodology.